NW Mental Illness Research, Education, and Clinical Center | Research Articles - 2016 - MIRECC / CoE
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NW Mental Illness Research, Education, and Clinical Center | Research Articles - 2016

2016 NW MIRECC Staff Research Articles and Presentations

NW MIRECC Research Articles:   In Press | 2019 | 2018 | 2017 | 2016 | 2015 | 2014

The findings of NW MIRECC research are disseminated through MIRECC Presents, lectures and presentations, and publications. Below is a list of publications and presentations by VISN 20 NW MIRECC researchers and fellowship program faculty that were published in 2016. Where available, a link to the full research article is provided at the end of the citation.

Barnett, P. G., Jeffers, A., Smith, M. W., Chow, B. K., McFall, M. E., & Saxon, A. J. (2016). Cost-effectiveness of
integrating tobacco cessation into Post-Traumatic Stress Disorder treatment. Nicotine & Tobacco Research, 18(3), 267-74. doi: 10.1093/ntr/ntv094

Blackie, L., Roepke, A., Hitchcott, N., & Joseph, S. (2016). Can people experience posttraumatic growth after committing
violent acts? Peace and Conflict: Journal of Peace Psychology, 22(4), 409-412. doi:10.1037/pac0000218

Boehnlein, J., & Hinton, D. E. (2016). From Shell Shock to Posttraumatic Stress Disorder and Traumatic Brain Injury:
A historical perspective on responses to combat trauma. In D. E. Hinton, & B. J. Good (Eds.), Culture and PTSD: Trauma in Global and Historical Perspective (pp. 100 - 101). Philadelphia, PA: University of Pennsylvania Press. (Full chapter not available for download)

Caska-Wallace, C., Katon, J., Lehavot, K., McGinn, M., & Simpson, T. L. (2016). Posttraumatic Stress Disorder symptom
severity and relationship functioning among partnered heterosexual and lesbian women veterans. LGBT Health, 3(3), 186-192. doi:10.1089/lgbt.2015.0097

Cubells, J. F., Schroeder, J. P., Barrie, E. S., Sadee, W., Berg, T., Mercer, K., … & Weinshenker, D. (2016). Human
bacterial artificial chromosome (BAC) transgenesis fully rescues noradrenergic function in dopamine-hydroxylase knockout mice. PlosOne, 11(5), e0154864.

Daniels, L. R., Boehnlein, J., & McCallion, P. (2016). The role of reminiscence and life review in healthy aging.
In D. B. Kaplan, & B. Berkman (Eds.), Handbook of Social Work in Health and Aging (pp. 100 - 101). New York, NY: Oxford University Press. (Full chapter not available for download)

Dedert, E., Resick, P. A., McFall, M. E., Dennis, P., Olsen, M., & Beckham, J. (2016). Pilot cases of combined cognitive
processing therapy and smoking cessation for smokers with posttraumatic stress disorder. Behavior Therapy, 47(1), 54-65. doi:10.1016/j.beth.2015.09.002

Del Razo, M., Morofuji, Y., Meabon, J., Huber, B., Peskind, E. R., Banks, W., … & Cook, D. G. (2016). Computational
and in vitro studies of blast-induced blood-brain barrier disruption. SIAM Journal on Scientific Computing, 38(3), B347-B374. doi:10.1137/15M1010750

Denneson, L., Kovas, A., Britton, P., Kaplan, M., McFarland, B., & Dobscha, S. (2016). Suicide risk documented during
veterans' last Veterans Affairs health care contacts prior to suicide. Suicide and Life-Threatening Behavior, 46(3), 363-374. doi:10.1111/sltb.12226

Dobscha, S. K., Lovejoy, T. I., Morasco, B. J., Kovas, A. E., Peters, D. M., Hart, K., ... McFarland, B. H. (2016). Predictors
of improvements in pain intensity in a national cohort of older veterans with chronic pain. Journal of Pain, 17(7), 824-835.

ABSTRACT: Little is known about the factors associated with pain-related outcomes in older adults. In this observational study, we sought to identify patient factors associated with improvements in pain intensity in a national cohort of older veterans with chronic pain. We included 12,924 veterans receiving treatment from the Veterans Health Administration with... Read full research article: Predictors of improvements in pain intensity in a national cohort of older veterans with chronic pain

Durazzo, T., Meyerhoff, D., Mon, A., Abé, C., Gazdzinski, S., & Murray, D. (2016). chronic cigarette smoking in healthy
middle-aged individuals is associated with decreased regional brain N-acetylaspartate and Glutamate levels. Biological Psychiatry, 79, 481-488. doi:10.1016/j.biopsych.2015.03.029

Eckerlin, D., Kovalesky, A., & Jakupcak, M. (2016). CE: Military sexual trauma in male service members. AJN, American
Journal of Nursing, 116(9), 34-43. doi:10.1097/01.NAJ.0000494690.55746.d9

Gibson, C. J., Gray, K. E., Katon, J., Simpson, T. L., & Lehavot, K. (2016). Sexual assault, sexual harassment, and
physical victimization during military service across age cohorts of women veterans. Women’s Health Issues, 26, 225-231.

Gilmore, A., Brignone, E., Painter, J., Lehavot, K., Fargo, J., Suo, Y., … & Gundlapalli, A. (2016). Military sexual
trauma and co-occurring posttraumatic stress disorder, depressive disorders, and substance use disorders among returning Afghanistan and Iraq veterans. Women's Health Issues, 26(5), 546-554. doi:10.1016/j.whi.2016.07.001

Glover, N., Sylvers, P., Shearer, E., Kane, M., Clasen, P., Epler, A., … & Jakupcak, M. (2016). The efficacy of
Focused Acceptance and Commitment Therapy in VA primary care. Psychological Services, 13(2), 156-161. doi:10.1037/ser0000062

Goodrich, D. G., Klingaman, E., Verchinina, L., Goldberg, R. W., Littman, A. J., Janney, C. A., … & Bowersox, N. W. (2016).
Sex differences in weight loss among veterans with serious mental illness: Observational study of a national weight management program. Women’s Health Issues, 26(4), 410-419.

Grossbard, J., Malte, C., Lapham, G., Pagulayan, K. F., Turner, A., Rubinsky, A., … & Saxon, A. J. (2016). Prevalence
of alcohol misuse and follow-up care in a national sample of OEF/OIF VA patients with and without TBI. Psychiatric Services. Advance Online Publication. doi:10.1176/appi.ps.201500290

Hall, K. S., Gregg, J., Bosworth, H. B., Beckham, J., Hoerster, K. D., Sloane, R., & Morey, M. C. (2016). Physical
activity counseling promotes physical and psychological resilience in older veterans with posttraumatic stress disorder. Mental Health and Physical Activity, 11, 53-59. doi:10.1016/j.mhpa.2016.10.001

Hendrickson, R. C., & Raskind, M. A. (2016). Noradrenergic dysregulation in the pathophysiology of PTSD.
Experimental Neurology, 284(Pt B), 181-195.

Hoerster, K. D., Wilson, S. M., Nelson, K. M., Reiber, G. E., & Masheb, R. (2016). Diet quality is associated
with mental health, social support, and neighborhood factors among Veterans. Eating Behaviors, 23, 168-173. doi: 10.1016/j.eatbeh.2016.10.003. PMID: 27816854

Huber, B., Meabon, J., Hoffer, Z., Zhang, J., Hoekstra, J., Pagulayan, K. F., … & Cook, D. G. (2016). Blast
exposure causes dynamic microglial/macrophage responses and microdomains of brain microvessel dysfunction. Neuroscience, 319, 206-220. doi:10.1016/j.neuroscience.2016.01.022

Kansagara, D., O’Neil, M., Nugent, S., Freeman, M., Low, A., Kondo, K., … & Morasco, B. (2016). Benefits and
harms of cannabis in chronic pain or post-traumatic stress disorder: a systematic review. VA ESP Project, #05, 225.

Klingaman, E. A., Hoerster, K. D., Aakre, J. M., Viverito, K. M., Medoff, D. R., & Goldberg, R. W. (2016). Veterans
with PTSD report more weight loss barriers than Veterans with no mental health disorders. General Hospital Psychiatry, 39, 1-7.

Lehavot, K., Rillamas-Sun, E., Weitlauf, J., Kimerling, R., Wallace, R. B., Sadler, A. G., … & Simpson, T. L. (2016).
Mortality in postmenopausal women by sexual orientation and veteran status. The Gerontologist, 56(Suppl. 1), S150-S162. doi:10.1093/geront/gnv125

Lehavot, K., Simpson, T. L., & Shipherd, J. (2016). Factors associated with suicidality among a national sample of
transgender veterans. Suicide and Life-Threatening Behavior, 46, 507-524. doi:10.1111/sltb.12233

Lehavot, K., Williams, E. C., Millard, S. P., Bradley, K. A., & Simpson, T. L. (2016). Association of alcohol misuse
with sexual identity and sexual behavior in women veterans. Substance Use and Misuse, 51, 216-229.

Liachko, N., Saxton, A., McMillan, P., Strovas, T., Currey, H., Taylor, L., … & Kraemer, B. C. (2016). The phosphatase
calcineurin regulates pathological TDP-43 phosphorylation. Acta Neuropathologica, 132(4), 545-561. doi:10.1007/s00401-016-1600-y

Lovejoy, T. I., Dobscha, S., Turk, D. C., Weimer, M. B., & Morasco, B. (2016). Correlates of prescription opioid
therapy in veterans with chronic pain and a history of substance use disorder. Journal of Rehabilitative Research and Development, 53, 25-36.

ABSTRACT: Patients with a history of substance use disorder (SUD) are more likely to be prescribed opioid medications for chronic pain than patients without substance use disorder (SUD) history; however, little is known about prescription opioid therapy in populations composed exclusively of patients with substance use disorder (SUD). This study examined correlates of prescription opioid therapy in 214 Veterans with chronic noncancer pain and substance use disorder (SUD) history. Read full research article: Correlates of prescription opioid therapy in Veterans with chronic pain and history of substance use disorder

Lu, M., Plagge, J., Marsiglio, M., & Dobscha, S. (2016). Clinician documentation on receipt of trauma-focused
evidence-based psychotherapies in a VA PTSD clinic. The Journal of Behavioral Health Services & Research, 43(1), 71-87. doi:10.1007/s11414-013-9372-9

Maguen, S., Hoerster, K. D., Littman, A. J., Klingaman, E., Evans-Hudnall, G., Holleman, R., … & Goodrich, D. E. (2016).
Iraq and Afghanistan veterans with PTSD participate less in VA’s weight loss program than those without PTSD. Journal of Affective Disorders, 193, 289-294. doi: 10.1016/j.jad.2015.12.078. Epub 2016 Jan 6.

McGinn, M. M., Hoerster, K. D., Stryczek, K. C., Malte, C., & Jakupcak, M. (2016). Relationship satisfaction, PTSD
symptom severity, and mental healthcare utilization among OEF/OIF veterans. Journal of Family Psychology. Advance Online Publication.

Meabon, J., de Laat, R., Ieguchi, K., Serbzhinsky, D., Hudson, M., Huber, B., … & Bothwell, M. (2016). Intracellular
LINGO-1 negatively regulates Trk neurotrophin receptor signaling. Molecular and Cellular Neuroscience, 70, 1-10. doi:10.1016/j.mcn.2015.11.002

Meabon, J., Huber, B., Cross, D., Richards, T., Minoshima, S., Pagulayan, K. F., … & Cook, D. G. (2016). Repetitive
blast exposure in mice and combat veterans causes persistent cerebellar dysfunction. Science Translational Medicine, 8(321), 321ra6-321ra6. doi: 10.1126/scitranslmed.aaa9585

Mooney, L. J., Hillhouse, M. P., Thomas, C., Ang, A., Sharma, G., Terry, G., … & Ling, W. (2016). Utilizing a two-stage
design to investigate the safety and potential efficacy of monthly Naltrexone plus once-daily Bupropion as a treatment for Methamphetamine Use Disorder. Journal of Addiction Medicine, 10(4), 236-43.

Morasco, B. J., Greaves, D. W., Lovejoy, T. I., Turk, D. C., Dobscha, S. K., & Hauser, P. (2016). Development and
preliminary evaluation of an integrated cognitive-behavior treatment for chronic pain and Substance Use Disorder in patients with the Hepatitis C virus. Pain Medicine, 17(12), 2280-2290.

ABSTRACT: Individuals with the hepatitis C virus (HCV) have high rates of both chronic pain and substance use disorder (SUD). Despite high comorbidity, there are limited data available on effective methods of treatment for co-occurring chronic pain and substance use disorder (SUD). In this study, we sought to develop and conduct preliminary testing of an integrated cognitive-behavior therapy (CBT) for chronic pain and substance use disorder (SUD) in patients with hepatitis C virus. Read full research article: Development and preliminary evaluation of an integrated cognitive-behavior treatment for chronic pain and Substance Use Disorder in patients with the Hepatitis C virus

Morasco, B. J., Peters, D., Krebs, E. E., Kovas, A. E., Hart, K., & Dobscha, S. K. (2016). Predictors of urine drug
testing for patients with chronic pain: Results from a national cohort of U.S. veterans. Substance Abuse, 37(1), 82-87.

ABSTRACT: Urine drug testing (UDT) is recommended for all patients who initiate chronic opioid therapy (COT) for the treatment of chronic pain; however, it is infrequently utilized. Some prior research has identified factors that may predict Urine drug testing (UDT), but studies have been limited. The purpose of this study is to examine the rate and predictors of Urine drug testing (UDT) among a national sample of patients with chronic pain who had new initiations of chronic opioid therapy (COT). Administrative data were examined for all veterans receiving medical care at Department of Veterans Affairs medical facilities who had new initiations of chronic opioid therapy (COT) during fiscal year 2011. Read full research article: Predictors of urine drug testing for patients with chronic pain: Results from a national cohort of U.S. veterans

Murray, D., & Durazzo, T. (2016). Frontal metabolite concentration deficits in opiate dependence relate to
substance use, cognition, and self-regulation. Journal of Addiction Research & Therapy, 7, 286. doi:10.4172/2155-6105.1000286

Niv, N., Frousakis, N., Tzucker, R. E., Dixon, L. B., & Glenn, S. (2016). A brief family intervention for depression
in primary care. Journal of Family Therapy. Advance Online Publication. doi:10.1111/1467-6427.12147

Norman, S., & Zaccari, B. (2016). PTSD consultation: Equipping providers to offer great care in or outside of the
VA. Traumatic Stress Points, International Society for Traumatic Stress Studies. Advance Online Publication.

Pagulayan, K. F., Temkin, N., Machamer, J., & Dikmen, S. (2016). Patterns of alcohol use after traumatic brain injury.
Journal of Neurotrauma, 33(14), 1390-1396. doi:10.1089/neu.2015.4071

Painter, J. M., Gray, K. E., McGinn, M., Mostoufi, S., & Hoerster, K. D. (2016). The relationships of Posttraumatic
Stress Disorder and depression symptoms with health-related quality of life and the role of social support among Veterans. Quality of Life Research, 25, 2657-67. doi:10.1007/s11136-016-1295-5

Palmer, B., & Raskind, M. A. (2016). Posttraumatic Stress Disorder and aging. The American Journal of Geriatric
Psychiatry, 24(3), 177-180. doi:10.1016/j.jagp.2016.01.133

Raskind, M. A., Millard, S., Petrie, E., Peterson, K., Williams, T. J., Hoff, D., … & Peskind, E. R. (2016). Higher
pretreatment blood pressure is associated with greater posttraumatic stress disorder symptom reduction in soldiers treated with prazosin. Biological Psychiatry, 80(10), 736–742. doi:10.1016/j.biopsych.2016.03.2108

Rasmussen, D. D., Johanson, S. S., & Kincaid, C. L. (2016). Melatonin treatment during alcohol withdrawal and
protracted deprivation reverses rat thyroid hormone dysregulation: correlation with startle response. Alcoholism: Clinical and Experimental Research, 40(S1), 35A.

Rasmussen, D. D., Johanson, S. S., Burns, J. L., & Kincaid, C. L. (2016). Reduction of a1- and ß-adrenergic signaling
at the time of traumatic stress reduces subsequent development of increased alcohol drinking in rats. Alcoholism: Clinical and Experimental Research, 40(S1), 198A.

Rodgman, C. J., Verrico, C. D., Holst, M., Thompson-Lake, D., Haile, C. N., La Garza, D., Raskind, M. A., & Newton, T.
F. (2016). Doxazosin XL reduces symptoms of Posttraumatic Stress Disorder in Veterans with PTSD: A pilot clinical trial. Journal of Clinical Psychiatry, 77(5), e561-e565.

Simoni, J., Smith, L., Oost, K., Lehavot, K., & Fredriksen-Goldsen, K. (2016). Disparities in physical health conditions
among lesbian and bisexual women: a systematic review of population-based studies. Journal of Homosexuality, 64(1), 32-44. doi:10.1080/00918369.2016.1174021

Simpson, T. L., Rillamas-Sun, E., Lehavot, K., Timko, C., Rubin, A., Cucciare, M. A., … & Hoggatt, K. J. (2016). Alcohol
consumption levels and all-cause mortality among women Veterans and non-Veterans enrolled in the women’s health initiative. The Gerontologist, 56(Suppl 1), S138-S149. doi: 10.1093/geront/gnv667

Takeda, S., Commins, C., DeVos, S., Nobuhara, C., Wegmann, S., Roe, A., … & Hyman, B. (2016). Seed-competent high-
molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients. Annals of Neurology, 80(3), 355-367. doi:10.1002/ana.24716

Vasterling, J. J., Aslan, M., Proctor, S., Ko, J., Marx, B. P., Jakupcak, M., … & Concato, J. (2016). Longitudinal
examination of posttraumatic stress disorder as a long-term outcome of Iraq War deployment. American Journal of Epidemiology, 184, 796-805. doi:10.1093/aje/kww151

Washington, D. L., Gray, K., Hoerster, K. D., Katon, J. G., Cochrane, B. B., La Monte, M. J., … & Tinker, L. (2016).
Trajectories in physical activity and sedentary time among women Veterans in the Women’s Health Initiative. The Gerontologist, 56 Suppl 1, S27-39.

Zaccari, B. (2016). Complementary integrative health in the movement towards transforming patient centered care in the
VA. Traumatic Stress Points, International Society for Traumatic Stress Studies. Retrieved from https://www.istss.org/education-research/traumatic-stresspoints/2016-june/military-matters-complementary-integrative-health.aspx

NW MIRECC Research Articles:   In Press | 2019 | 2018 | 2017 | 2016 | 2015 | 2014