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MIRECC Role(s): MIRECC Co-Associate Director for Research, Fellowship Director (Physician Training Track), Fellowship Primary Mentor
Bio: Dr. Sweet is currently Professor of Psychiatry and Neurology
at the University of Pittsburgh and Co-Associate Director for Research at the Mental Illness Research, Education, and Clinical Center
(MIRECC), VA Pittsburgh Healthcare System (VAPHS). In addition to his role as MIRECC Fellowship Director (Physician Training Track), Dr. Sweet also directs
a postdoctoral fellowship training program (T32) in the University of Pittsburgh Department of Psychiatry, focused on training in the translational
neuroscience of mental illness.
He earned his BS in Biology from Rensselaer Polytechnic Institute and his MD
from the University of Maryland. Dr. Sweet is a fellow of the American College of Neuropsychopharmacology and a
member of the Society of Biologic Psychiatry, and is a Founding Member of the International
College of Geriatric Psychoneuropharmacology.
He has received awards for his research and teaching, among them the 2005 Mentorship Award
from the University of Pittsburgh Department of Psychiatry.
Research Interests: Dr. Sweet's research is focused on
understanding the mechanisms which lead to the generation of psychotic symptoms which are core features of the prototypic psychotic disorder,
schizophrenia, but also occur in about 50% of individuals with Alzheimer's disease. In his work, he has proposed that there are common genetic
risk factors and vulnerable brain circuits that act together to cause positive symptoms across these disorders.