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Bupropion SR (Zyban®/Wellbutrin®)

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* Follow the instructions of your primary care provider for the proper dosage and use of bupropion.

  1. Take bupropion as directed. Do not crush, chew, or divide tablets.
  2. Bupropion is usually taken as a 150mg tablet for 8 to 12 weeks, starting before your Quit Date:

    Days 1-3: 1 tablet in the morning

    Starting Day 4: 1 tablet in the morning and 1 tablet in the afternoon

  3. Make sure to have 8 hours between each dose. Take the first dose when you wake up in the morning and the second dose 8 hours later. Try to avoid taking the second dose late at night otherwise you might have trouble sleeping.
  4. If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
  5. Bupropion can be used together with the nicotine patch, or you can use nicotine gum or nicotine lozenges when you have strong cravings.

Do not take bupropion if you:

Side effects