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VISN 1 New England MIRECC Publications: Genetic Factors & Neurobiology

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Genetic Factors & Neurobiology

Arias, A.J., Gelernter, J., Gueorguieva, R., Ralevski, E., & Petrakis, I.L. (2014). Pharmacogenetics of naltrexone and disulfiram in alcohol dependent, dually diagnosed Veterans. The American Journal on Addictions, 23(3), 288-293. 

Arout, C.A., Edens, E., Petrakis, I., & Sofuoglu, M. (2015). Targeting opioid-induced hyperalgesia in clinical treatment: Neurobiological considerations. CNS Drugs, 29(6), 465-486.

Carroll, K.M., Herman, A., DeVito, E.E., Frankforter, T.L., Potenza, M.N., & Sofuoglu, M. (2015). Catehol-o-methyltransferase gene Val158Met polymorphism as a potential predictor of response to computer-assisted delivery of cognitive-behavioral therapy among cocaine-dependent individuals: Preliminary findings from a randomized controlled trial. The American Journal on Addictions, 24(5), 443-451. 

Gomez, R., Behar, K.L., Watzl, J., Weinzimer, S.A., Gulanski, B., Sanacora, G., Koretski, J., Guidone, E., Jiang, L.H., Petrakis, I., Pittman, B., Krystal, J.H. & Mason, G.F. (2012). Intravenous ethanol infusion decreases human cortial gamma-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spetroscopy at 4 tesla. Biological Psychiatry, 71(3), 239-246. 

Herman, A.I., DeVito, E.E., Jensen, K.P., & Sofuoglu, M. (2014). Pharmacogenetics of nicotine addiction: Role of dopamine. Pharmacogenomics, 15(2), 221-234. 

Herman, A.I., Jatlow, P.I., Gelernter, J., Listman, J.B., & Sofuoglu, M. (2013). COMT Val158MET modulates subjective responses to intravenous nicotine and cognitive performance in abstinent smokers. Pharmacogenomics, 13(6), 490-497. 

Jensen, K.P., DeVito, E.E., Herman, A.I., Valentine, G.W., Gelernter, J., & Sofuoglu, M. (2015). A CHRNA5 smoking risk variant decreases the aversive effects of nicotine in humans. Neuropsychopharmacology, 40, 2813-2821.

Jensen, K.P., Herman, A.I., Morean, M.E., Kranzler, H.R., Gelernter, J., & Sofuoglu, M. (2015). FKBP5 variation is associated with the acute and chronic effects of nicotine. Pharmacogenomics Journal, 15(4), 340-346. 

Jensen, K.P., Smith, A.H., Herman, A.I., Farrer, L.A., Kranzler, H.R., Sofuoglu, M., & Gelernter, J. (2016). A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke. Molecular Psychiatry22(2), 242-249. 

Jensen, K.P. & Sofuoglu, M. (2016). Stress response genes and the severity of nicotine withdrawal. Pharmacogenomics, 17(1), 1-3.

Kraus, S.W., Voon, V., & Potenza, M.N. (2016). Neurobiology of compulsive sexual behavior: Emerging science. Neuropsychopharmacology Reviews, 41, 385-386. 

Li, D., Zhao, H., & Gelernter, J. (2012). Further clarification of the contribution of the ADH1C gene to vulnerability of alcoholism and selected liver diseases. Human Genetics, 131(8), 1361-1374. 

Neumeister, A., Normandin, M.D., Pietrzak, R.H., Piomelli, D., Zheng, M-Q., Gujarro-Anton, A., Potenza, M.N., Bailey, C.R., Lin, S-F., Najafzadeh, S., Ropchan, J., Henry, S., Corsi-Travali, S., Carson, R.E., & Huang, Y. (2013). Increased OMAR MA1 DV in PTSD. Molecular Psychiatry, 18, 1034-1040. 

Papas, R.K., Gakinya, B.N., Mwaniki, M.M., Keter, A.K., Lee, H., Loxley, M.P., Klein, D.A., Sidle, J.E., Martino, S., Baliddawa, J.B., Schlaudt, K.L.,& Maisto, S.A. (2016). Associations between the phosphatidylethanol alcohol biomarker and self-reported alcohol use in a sample of HIV-infected outpatient drinkers in western Kenya. Alcoholism: Clinical and Experimental Research, 40(8), 1779–1787.

Pietrzak, R.H., Huang, Y., Corsi-Travali, S., Zheng, M.Q., Lin, S.F., Henry, S., Potenza, M.N., Piomelli, D., Carson, R.E., & Neumeister, A. (2014). Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. Neuropsychopharmacology, 39(11), 2519-2528.

Pietrzak, R.H., Naganawa, M., Huang, Y., Corsi-Travali, S., Zheng, M.Q., Stein, M.B., Henry, S., Lim, K., Ropchan, J., Lin, S.F., Carson, R.E., & Neumeister, A. (2014). Association of in vivo kappa-opioid receptor availability and the transdiagnostic dimensional expression of trauma-related psychopathology. JAMA Psychiatry, 71(11), 1262-1270.

Leeman, R.F., & Potenza, M.N. (2013). A targeted review of the neurobiology and genetics of behavioral addictions: An emerging area of research. Canadian Journal of Psychiatry, 58(5), 260-273.

Xie, P., Kranzler, H.R., Farrer, L., & Gelernter, J. (2012). Serotonin transporter 5-HTTLPR genotype moderates the effects of childhood adversity on post-traumatic stress disorder risk: A replication study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 159B(6), 644-652. 

Xie, P., Kranzler, H.R., Zhang, H., Oslin, D., Anton, R.F., Farrer, L.A., & Gelernter, J. (2012). Childhood adversity increases risk for nicotine dependence and interacts with alpha-5 nicotinic acetylcholine receptor genotype specifically in males. Neuropsychopharmacology, 37, 669-676. 

Yoon, G., Pittman, B., Limoncelli, D., Krystal, J.H., & Petrakis, I.L. (2016). Familial alcoholism risk and the ratio of stimulant to sedative effects of ketamine. Biological Psychiatry, 79(9), e69-e70.

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Mehmet Sofuoglu, M.D., Ph.D.

Patricia Sweeney, Psy.D., CPRP
Director for Education

Richard Carson, LCSW
Administrative Officer
203-932-5711 Ext. 4338

Ilan Harpaz-Rotem, Ph.D.
Co-Director for MIRECC Fellowship Program
203-932-5711 Ext. 2599

Suzanne Decker, Ph.D.
Co-Director for MIRECC Fellowship Program
203-932-5711 Ext. 7425