Attention A T users. To access the menus on this page please perform the following steps. 1. Please switch auto forms mode to off. 2. Hit enter to expand a main menu option (Health, Benefits, etc). 3. To enter and activate the submenu links, hit the down arrow. You will now be able to tab or arrow up or down through the submenu options to access/activate the submenu links.

MIRECC / CoE

Menu
Menu

Quick Links

Veterans Crisis Line Badge
My healthevet badge
EBenefits Badge
 

PRIME Care Study

The purpose of this study is to determine the effectiveness of providing depressed Veterans and their providers the results of pharmacogenetic (PGx) testing for psychotropic medications. The study focuses on whether and how patients and providers use genetic test results given to them at the time an antidepressant is to be initiated to treat Major Depressive Disorder (MDD) and whether use of the test results improves patient outcomes. MDD is one of the most common conditions associated with military service and combat exposure, increases suicide risk, and worsens the course of common medical conditions, making it a leading cause of disability and mortality. Validation of a PGx test to personalize the treatment of MDD represents an important opportunity to improve the healthcare of Veterans.  Veteran recruitment will take place at 19 different VA Sites.      

Introduction to Pharmacogenetics: PRIME Care Study: https://youtu.be/X5atvMqPAUY
This whiteboard video briefly explains pharmacogenetics, what it is, and how it is being used in healthcare today. The role of pharmacogenetics in the VA PRIME Care study is described. Running time: 2:59
Intended Audience: Patients and Providers


PRIME Care Study Introduction: https://youtu.be/U_TXIWypb6E
This video summarizes the VA PRIME Care study, including public health significance, study design, the pharmacogenetic test used, study hypotheses and future directions.  
Running time: 21:59
Intended Audience: Providers


Introduction to Pharmacogenetic Testing for Providers: https://youtu.be/h6MbeaEUNn0
This video provides an introduction to pharmacogenetics and discusses the potential application of pharmacogenetics to the mental health field. An overview of the VA PRIME Care study is presented
Running time: 5:42
Intended Audience: Providers


Using Your Patient Test Results: https://youtu.be/qOsAxI0uOPA
Utilizing four case examples, this video walks through the application of pharmacogenetic test results used in the VA PRIME Care Study.
Running time: 14:47
Intended Audience: Providers


Talking to Your Patients About Test Results: https://youtu.be/1TmqoG16lJI
Through the use of vignettes, this video provides guidance to providers on how to talk to their patients about the pharmacogenetic test used in the VA PRIME Care study and approaches for reviewing the results.
Running time: 15:01
Intended Audience: Providers


VA PRIME Care Playlist:https://www.youtube.com/playlist?list=PL3AQ_JVoBEyyRPLVhZ8NjgL9J3HU4jZ4d

To find out which VA Medical Centers are participating in this study and the local contact information for each, click here.

ClinicalTrials.gov ID: NCT03170362

 

Contact

David W. Oslin, M.D.
Principal Investigator
CPL Michael J Crescenz VA Medical Center
215-823-5894
dave.oslin@va.gov

Erin Ingram
Senior Research Coordinator
CPL Michael J Crescenz VA Medical Center
215-823-5800 Ext. 2895
Erin.Ingram@va.gov