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PRIME Care Study

The purpose of this study is to determine the effectiveness of providing depressed Veterans and their providers the results of pharmacogenetic (PGx) testing for psychotropic medications. The study focuses on whether and how patients and providers use genetic test results given to them at the time an antidepressant is to be initiated to treat Major Depressive Disorder (MDD) and whether use of the test results improves patient outcomes. MDD is one of the most common conditions associated with military service and combat exposure, increases suicide risk, and worsens the course of common medical conditions, making it a leading cause of disability and mortality. Validation of a PGx test to personalize the treatment of MDD represents an important opportunity to improve the healthcare of Veterans.  Veteran recruitment will take place at 19 different VA Sites.     

Introduction to Pharmacogenetics: PRIME Care Study:

Introduction to Pharmacogenetic Testing for Providers:

To find out which VA Medical Centers are participating in this study and the local contact information for each, click here. ID: NCT03170362



David W. Oslin, M.D.
Principal Investigator
CPL Michael J Crescenz VA Medical Center

Erin Ingram
Senior Research Coordinator
CPL Michael J Crescenz VA Medical Center
215-823-5800 Ext. 2895