PRIME Care Study
 |
PRIME Care Dissemination to Date
(updated 7/12/2022)
Peer-Reviewed Journal Articles
Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission
of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial [link]
Journal of the American Medical Association | July 2022
Daily Steps and Depressive Symptoms: A Longitudinal Evaluation of Patients with Major Depressive Disorder in the Precision Medicine in Mental Health Care Study [link]
Journal of Affective Disorders | January 2022
Christine M. Ramsey, PhD; Kevin G. Lynch, PhD; Philip R. Gehrman, PhD; Srinivasan Vairavan, PhD; Vaibhav A. Narayan, PhD, MBA; Qingqin S. Li, PhD; David W. Oslin, MD
Study Design and Implementation of the PRecision Medicine In MEntal health Care (PRIME Care) Trial. [link]
Contemporary Clinical Trials | February 2021
David W. Oslin, MD; Sara R. Chapman, MS, OTR/L; Scott L. Duvall, PhD; Joel Gelernter, MD; Erin P. Ingram; Henry R. Kranzler, MD; Lisa S. Lehmann, MD; Julie A. Lynch, PhD, RN; Kevin G. Lynch, PhD; Jeffrey M. Pyne, MD; Mei-Chiung Shih, PhD; Annjanette Stone; Michael E. Thase, MD; Laura O. Wray, PhD
Prevalence of Predicted Gene-Drug Interactions for Antidepressants in the Treatment of Major Depressive Disorder in the Precision Medicine in Mental Health Care Study [link]
Journal of Affective Disorders | 2021
Christine M. Ramsey, PhD; Kevin G. Lynch, PhD; Michael E. Thase, MD; Joel Gelernter, MD; Henry R. Kranzler, MD; Jeffrey M. Pyne, MD; Ming-Chieh Shih, MD, PhD; Annjanette Stone; David W. Oslin, MD
Primary Care and Mental Health Providers' Perceptions of Implementation of Pharmacogenetics Testing for Depression Prescribing [link]
BMC Psychiatry | October 28, 2020
Bonnie M. Vest, PhD; Laura O. Wray, PhD; Laura A. Brady, PhD; Michael E. Thase, MD; Gregory P. Beehler, PhD; Sara R. Chapman, MS, OTR/L; Leland E. Hull, MD; David W. Oslin, MD
Early Adoption of Pharmacogenetic Testing for Veterans Prescribed Psychotropic Medications [link]
Pharmacogenomics | August 8, 2019
Leland E. Hull, Catherine Chanfreau-Coffinier, PhD; Sony Tuteja, PharmD; Dan Berlowitz, MD; Lisa S. Lehmann, MD; David W. Oslin, MD; Jeffrey M. Pyne, MD; Scott L. Duvall, PhD; Julie A. Lynch, PhD, RN
Projected Prevalance of Actionable Pharmacogenetic Variants and Level A Drugs Prescribed Among U.S. Veterans Health Administration Pharmacy Users [link]
JAMA Network Open | June 7, 2019
Catherine Chanfreau-Coffinier, PhD; Leland E. Hull, MD; Julie A. Lynch, PhD, RN; Scott L. Duvall, PhD; Scott M. Damrauer, Franscesca E. Cunningham, PharmD; Benjamin F. Voight, PhD; Michael E. Matheny, MD; David W. Oslin, MD; Michael S. Icardi, MD; Sony Tuteja, PharmD
Gene-Based Prescribing is Here. Are Providers Ready? [link]
American Journal of Medicine | March 12, 2019
Leland E. Hull, MD; Lisa S. Lehmann, MD; Julie A. Lynch, PhD, RN
VA Primary Care and Mental Health Providers' Comfort with Genetic Testing: Survey Results from the PRIME Care Study [link]
Journal of General Internal Medicine | January 2, 2019
Leland E. Hull, MD; Kevin G. Lynch, PhD; David W. Oslin, MD
Oral Presentations
Primary Care and Mental Health Provider Perceptions of Pharmacogenetic Testing for Depression: Qualitative Results from PRIME Care Study Focus Groups
HSR&D/QUERI 2019 National Conference (Washington, D.C.) | October 30, 2019
Laura O. Wray, PhD; Bonnie M. Vest, PhD; Laura A. Brady, PhD; Leland E. Hull, MD; Gregory P. Beehler, PhD; Sara R. Chapman, MS, OTR/L; Michael E. Thase, MD; David W. Oslin, MD
Poster Presentations
Implementation Data During a Pragmatic Clinical Trial to Inform Future Implementation Strategies: Results from PRIME Care
13th Annual Conference on the Science of Dissemination and Implementation (Virtual) | December 15-17, 2020
Bonnie M. Vest, PhD; Laura O. Wray, PhD; Gregory P. Beehler, PhD, MA; Leland E. Hull, MD, MPH; Laura A. Brady, PhD; Sara R. Chapman, MS, OTR/L; Michael E. Thase, MD
Integrating Implementation Science (IS) into an RCT: PRIME Care
AcademyHealth Annual Conference on the Science of Dissemination and Implementation in Health (Washington, D.C.) | December 14-16, 2019
Laura O. Wray, PhD; David W. Oslin, MD; Gregory P. Beehler, PhD, MA; Bonnie M. Vest, PhD; Laura A. Brady, PhD; Leland E. Hull, MD, MPH; Michael E. Thase, MD; Sara R. Chapman, MS, OTR/L; Andrea Ford
Identifying Provider Characteristics Associated with Patient Referral for Pharmacogenetic Testing: A Quantitative Analysis from the PRIME Care Study
HSR&D/QUERI 2019 National Conference (Washington, D.C.) | October 30, 2019
Christine M. Ramsey, PhD; Leland E. Hull, MD; Kevin G. Lynch, PhD; David W. Oslin, MD
Developing a Strategic Implementation Plan for Pre-emptive Pharmacogenomic Testing in the Department of Veterans Affairs
Clinical Pharmacogenetics Implementation Consortium (CPIC) Meeting (Memphis) | June 6, 2019
Julie A. Lynch, PhD; Kyung Min Lee, PhD; Leland E. Hull, MD; Catherine Chanfreau-Coffinier, PhD; Scott L. DuVall, PhD; Sony Tuteja, PharmD; David W. Oslin MD; Michael S. Icardi, MD; Michael Kelley, MD; Deepak Voora, MD
Integrating Implementation Science into a Large Pharmacogenetics Trial: The VA Precision Medicine in Mental Health Care Study
AcademyHealth Annual Research Meeting (Washington, D.C.) | June 3, 2019
Laura O. Wray, PhD; David W. Oslin, MD; Bonnie Vest, PhD; Sara Chapman, MS, OTR/L; Laura Brady, PhD
Projecting the Impact of Pharmacogenetics on Veteran Pain Management
AcademyHealth Annual Research Meeting (Washington, D.C.) | June 3, 2019
Catherine Chanfreau-Coffinier, PhD; Julie A. Lynch, PhD; Leland E. Hull, MD; David W. Oslin MD; Sony Tuteja, PharmD
Predicted Prevalance of Actionable Pharmacogenetic Variants and Associated Drug Use in the VHA Patient Population: Impact and Implications of Adopting Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Treatment of Veterans
American Society of Human Genetics Annual Meeting (San Diego) | Oct. 15-16, 2018
Leland E. Hull, MD; Sony Tuteja, PharmD; Catherine Chanfreau-Coffinier, PhD; Olga Efimova, MD, PhD; David W. Oslin, MD; Gregorio Coronado; Scott L. DuVall, PhD; Julie A. Lynch, PhD
Utilization and Impact of a Psychiatric Pharmacogenetic Panel in the Department of Veterans Affairs
American Society of Human Genetics Annual Meeting (San Diego) | October 15-16, 2018
34th International Conference on Pharmacoepidemiology | Aug. 22-26, 2018
Leland E. Hull, MD; Sony Tuteja, PharmD; Catherine Chanfreau-Coffinier, PhD; Olga Efimova, MD, PhD; David W. Oslin, MD; Gregorio Coronado; Scott L. DuVall, PhD; Julie A. Lynch, PhD
ClinicalTrials.gov ID: NCT03170362
