2022 Research Articles
2022 VISN 20 MIRECC Staff Research Articles and Presentations
The findings of NW MIRECC research are disseminated through MIRECC Presents, lectures and presentations, and publications. Below is a list of publications and presentations by VISN 20 NW MIRECC researchers and fellowship program faculty that were published in 2022.
Adeniyi, P., Fopiano, K., Banine, F., Garcia, M., Gong, X., Keene, C., Sherman, L., Bagi, Z., & Back, S. (2022). Multispectral LEDs Eliminate Lipofuscin-Associated Autofluorescence for Immunohistochemistry and CD44 Variant Detection by in Situ Hybridization in Aging Human, non-Human Primate, and Murine Brain. ASN Neuro, 14, 175909142211231. doi:10.1177/17590914221123138
Alosco, M., Mariani, M., Adler, C., Balcer, L., Bernick, C., Au, R., Banks, S., Barr, W., Bouix, S., Cantu, R., Coleman, M., Dodick, D., Farrer, L., Geda, Y., Katz, D., Koerte, I., Kowall, N., Lin, A., Marcus, D., Marek, K., McClean, M., McKee, A., Mez, J., Palmisano, J., Peskind, E. R., Tripodis, Y., Turner, R., Wethe, J., Cummings, J., Reiman, E., Shenton, M., Stern, R., Adler, C., Alosco, M., Au, R., Balcer, L., Banks, S., Barr, W., Bernick, C., Bouix, S., Cantu, R., Chen, K., Coleman, M., Cummings, J., Dodick, D., Farrer, L., Fitzsimmons, J., Geda, Y., Goldberg, J., Helm, R., Johnson, K., Katz, D., Kirov, I., Koerte, I., Kowall, N., Lin, A., Lui, Y., Marcus, D., Marek, K., Mariani, M., Marmar, C., McClean, M., McKee, A., Mez, J., Miller, J., Palmisano, J., Pasternak, O., Peskind, E. R., Protas, H., Reiman, E., Ritter, A., Shenton, M., Stern, R., Su, Y., Tripodis, Y., Turner, R., Weller, J., & Wethe, J. (2021). Developing methods to detect and diagnose chronic traumatic encephalopathy during life: rationale, design, and methodology for the DIAGNOSE CTE Research Project. Alzheimer's Research and Therapy, 13 (1), 136. doi:10.1186/s13195-021-00872-x
Alosco, M., Su, Y., Stein, T., Protas, H., Cherry, J., Adler, C., Balcer, L., Bernick, C., Pulukuri, S., Abdolmohammadi, B., Coleman, M., Palmisano, J., Tripodis, Y., Mez, J., Rabinovici, G., Marek, K., Beach, T., Johnson, K., Huber, B., Koerte, I., Lin, A., Bouix, S., Cummings, J., Shenton, M., Reiman, E., McKee, A., Stern, R., Reiman, E., Su, Y., Chen, K., Protas, H., Boker, C., Alosco, M., Au, R., Cantu, R., Farrer, L., Helm, R., Katz, D., Kowall, N., Mez, J., Mercier, G., Otis, J., Stern, R., Weller, J., Simkin, I., Andino, A., Conneely, S., Diamond, C., Fagle, T., Haller, O., Hunt, T., Gullotti, N., Mariani, M., Mayville, B., McLaughlin, K., Nanna, M., Platt, T., Pulukuri, S., Rice, F., Sestak, M., McClean, M., Tripodis, Y., Annis, D., Chaisson, C., Dixon, D., Finney, C., Gallagher, K., Hartlage, K., Lu, J., Martin, B., Ojo, E., Palmisano, J., Pine, B., Ramachandran, J., Bouix, S., Fitzsimmons, J., Lin, A., Koerte, I., Pasternak, O., Shenton, M., Arcinieago, H., Billah, T., Bonke, E., Breedlove, K., Coello, E., Coleman, M., Jung, L., Liao, H., Loy, M., Rizzoni, E., Schultz, V., Silva, A., Vessey, B., Wiegand, T., Banks, S., Bernick, C., Miller, J., Ritter, A., Sabbagh, M., de la Cruz, R., Durant, J., Golceker, M., Harmon, N., Kaylegian, K., Long, R., Nance, C., Sandoval, P., Turner, R., Marek, K., Serrano, A., Adler, C., Dodick, D., Geda, Y., Wethe, J., Falk, B., Duffy, A., Howard, M., Montague, M., Osgood, T., Babcock, D., Bellgowan, P., Balcer, L., Barr, W., Goldberg, J., Wisniewski, T., Kirov, I., Lui, Y., Marmar, C., Hasanaj, L., Serrano, L., Al-Kharafi, A., George, A., Martin, S., Riley, E., Runge, W., Cummings, J., Peskind, E. R., Colasurdo, E., Marcus, D., Gurney, J., Greenwald, R., & Johnson, K. (2022). Associations between near end-of-life flortaucipir PET and postmortem CTE-related tau neuropathology in six former American football players. European Journal of Nuclear Medicine and Molecular Imaging. Advance online publication. doi:10.1007/s00259-022-05963-x
Ameen-Ali, K., Bretzin, A., Lee, E., Folkerth, R., Hazrati, L., Iacono, D., Keene, C., Kofler, J., Kovacs, G., Nolan, A., Perl, D., Priemer, D., Smith, D., Wiebe, D., Stewart, W., Al-Sarraj, S., Cortes, E., Crary, J., Dams-O’Connor, K., Diaz-Arrastia, R., Dollé, J., Edlow, B., Fischl, B., Hinds, C., Johnson, V., Manley, G., Meaney, D., Okonkwo, D., Schneider, A., Schneider, J., Troakes, C., Trojanowski, J., van der Kouwe, A., & Yaffe, K. (2022). Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change. Acta Neuropathologica Communications, 10 (1), 1-50. doi:10.1186/s40478-022-01353-4
Bagi, Z., Kroenke, C., Fopiano, K., Tian, Y., Filosa, J., Sherman, L., Larson, E., Keene, C., Degener O’Brien, K., Adeniyi, P., & Back, S. (2022). Association of cerebral microvascular dysfunction and white matter injury in Alzheimer’s disease. GeroScience. Advance online publication. doi:10.1007/s11357-022-00585-5
Bakken, T., Jorstad, N., Hu, Q., Lake, B., Tian, W., Kalmbach, B., Crow, M., Hodge, R., Krienen, F., Sorensen, S., Eggermont, J., Yao, Z., Aevermann, B., Aldridge, A., Bartlett, A., Bertagnolli, D., Casper, T., Castanon, R., Crichton, K., Daigle, T., Dalley, R., Dee, N., Dembrow, N., Diep, D., Ding, S., Dong, W., Fang, R., Fischer, S., Goldman, M., Goldy, J., Graybuck, L., Herb, B., Hou, X., Kancherla, J., Kroll, M., Lathia, K., van Lew, B., Li, Y., Liu, C., Liu, H., Lucero, J., Mahurkar, A., McMillen, D., Miller, J., Moussa, M., Nery, J., Nicovich, P., Niu, S., Orvis, J., Osteen, J., Owen, S., Palmer, C., Pham, T., Plongthongkum, N., Poirion, O., Reed, N., Rimorin, C., Rivkin, A., Romanow, W., Sedeño-Cortés, A., Siletti, K., Somasundaram, S., Sulc, J., Tieu, M., Torkelson, A., Tung, H., Wang, X., Xie, F., Yanny, A., Zhang, R., Ament, S., Behrens, M., Bravo, H., Chun, J., Dobin, A., Gillis, J., Hertzano, R., Hof, P., Höllt, T., Horwitz, G., Keene, C., Kharchenko, P., Ko, A., Lelieveldt, B., Luo, C., Mukamel, E., Pinto-Duarte, A., Preissl, S., Regev, A., Ren, B., Scheuermann, R., Smith, K., Spain, W., White, O., Koch, C., Hawrylycz, M., Tasic, B., Macosko, E., McCarroll, S., Ting, J., Zeng, H., Zhang, K., Feng, G., Ecker, J., Linnarsson, S., & Lein, E. (2021). Comparative cellular analysis of motor cortex in human, marmoset and mouse. Nature, 598 (7879), 111-119. doi:10.1038/s41586-021-03465-8
Balba, N., McBride, A., Callahan, M., Mist, S., Jones, K., Butler, M., Lim, M., & Heinricher, M. (2022). Photosensitivity Is Associated with Chronic Pain following Traumatic Brain Injury. Journal of Neurotrauma, 39 (17-18), 1183-1194. doi:10.1089/neu.2022.0019
Baskin, B., Lee, S., Skillen, E., Wong, K., Rau, H., Hendrickson, R. C., Pagulayan, K. F., Raskind, M. A., Peskind, E. R., Phillips, P., Cook, D. G., & Schindler, A. (2021). Repetitive Blast Exposure Increases Appetitive Motivation and Behavioral Inflexibility in Male Mice. Frontiers in Behavioral Neuroscience, 15, 792648. doi:10.3389/fnbeh.2021.792648
Berg, J., Sorensen, S., Ting, J., Miller, J., Chartrand, T., Buchin, A., Bakken, T., Budzillo, A., Dee, N., Ding, S., Gouwens, N., Hodge, R., Kalmbach, B., Lee, C., Lee, B., Alfiler, L., Baker, K., Barkan, E., Beller, A., Berry, K., Bertagnolli, D., Bickley, K., Bomben, J., Braun, T., Brouner, K., Casper, T., Chong, P., Crichton, K., Dalley, R., de Frates, R., Desta, T., Lee, S., D’Orazi, F., Dotson, N., Egdorf, T., Enstrom, R., Farrell, C., Feng, D., Fong, O., Furdan, S., Galakhova, A., Gamlin, C., Gary, A., Glandon, A., Goldy, J., Gorham, M., Goriounova, N., Gratiy, S., Graybuck, L., Gu, H., Hadley, K., Hansen, N., Heistek, T., Henry, A., Heyer, D., Hill, D., Hill, C., Hupp, M., Jarsky, T., Kebede, S., Keene, L., Kim, L., Kim, M., Kroll, M., Latimer, C., Levi, B., Link, K., Mallory, M., Mann, R., Marshall, D., Maxwell, M., McGraw, M., McMillen, D., Melief, E., Mertens, E., Mezei, L., Mihut, N., Mok, S., Molnar, G., Mukora, A., Ng, L., Ngo, K., Nicovich, P., Nyhus, J., Olah, G., Oldre, A., Omstead, V., Ozsvar, A., Park, D., Peng, H., Pham, T., Pom, C., Potekhina, L., Rajanbabu, R., Ransford, S., Reid, D., Rimorin, C., Ruiz, A., Sandman, D., Sulc, J., Sunkin, S., Szafer, A., Szemenyei, V., Thomsen, E., Tieu, M., Torkelson, A., Trinh, J., Tung, H., Wakeman, W., Waleboer, F., Ward, K., Wilbers, R., Williams, G., Yao, Z., Yoon, J., Anastassiou, C., Arkhipov, A., Barzo, P., Bernard, A., Cobbs, C., de Witt Hamer, P., Ellenbogen, R., Esposito, L., Ferreira, M., Gwinn, R., Hawrylycz, M., Hof, P., Idema, S., Jones, A., Keene, C., Ko, A., Murphy, G., Ng, L., Ojemann, J., Patel, A., Phillips, J., Silbergeld, D., Smith, K., Tasic, B., Yuste, R., Segev, I., de Kock, C., Mansvelder, H., Tamas, G., Zeng, H., Koch, C., & Lein, E. (2021). Human neocortical expansion involves glutamatergic neuron diversification. Nature, 598 (7879), 151-158. doi:10.1038/s41586-021-03813-8
Boase, K., Machamer, J., Temkin, N., Dikmen, S., Wilson, L., Nelson, L., Barber, J., Bodien, Y., Giacino, J., Markowitz, A., McCrea, M., Satris, G., Stein, M., Taylor, S., Manley, G., Adeoye, O., Bullock, M., Corrigan, J., Diaz-Arrastia, R., Ellenbogen, R., Feeser, V., Ferguson, A., Gardner, R., Goldman, D., Gopinath, S., Hemphill, J., Keene, C., Korley, F., Kramer, J., Kreitzer, N., Levin, H., Lindsell, C., Madden, C., Martin, A., McAllister, T., Merchant, R., Mukherjee, P., Ngwenya, L., Noel, F., Nolan, A., Okonkwo, D., Palacios, E., Perl, D., Puccio, A., Rabinowitz, M., Robertson, C., Rosand, J., Sander, A., Schnyer, D., Seabury, S., Sherer, M., Toga, A., Valadka, A., Vassar, M., MS, R., Vespa, P., Wang, K., Yue, J., Yuh, E., & Zafonte, R. (2021). Central Curation of Glasgow Outcome Scale-Extended Data: Lessons Learned from TRACK-TBI. Journal of Neurotrauma, 38 (17), 2419-2434. doi:10.1089/neu.2020.7528
Boehnlein, J., & Kinzie, J. (2021). Experiencing Mental Illness: Suffering, Hope, and Healing. Narrative Inquiry in Bioethics, 11 (2), 189-194. doi:10.1353/nib.2021.0070
Bohr, T., Hjorth, P., Holst, S., Hrabetová, S., Kiviniemi, V., Lilius, T., Lundgaard, I., Mardal, K., Martens, E., Mori, Y., Nägerl, U., Nicholson, C., Tannenbaum, A., Thomas, J., Tithof, J., Benveniste, H., Iliff, J. J., Kelley, D., & Nedergaard, M. (2022). The glymphatic system: Current understanding and modeling. iScience, 25 (9), 104987. doi:10.1016/j.isci.2022.104987
Brett, B., Gardner, R., Godbout, J., Dams-O’Connor, K., & Keene, C. (2022). Traumatic Brain Injury and Risk of Neurodegenerative Disorder. Biological Psychiatry, 91(5), 498-507. doi:10.1016/j.biopsych.2021.05.025
Burke, B., Latimer, C., Keene, C., Sonnen, J., McCormick, W., Bowen, J., McCurry, S., Larson, E., & Crane, P. (2021). Theoretical impact of the AT(N) framework on dementia using a community autopsy sample. Alzheimer's & Dementia, 17(12), 1879-1891. doi:10.1002/alz.12348
Burke, J., Gugger, J., Ding, K., Kim, J., Foreman, B., Yue, J., Puccio, A., Yuh, E., Sun, X., Rabinowitz, M., Vassar, M., Taylor, S., Winkler, E., Deng, H., McCrea, M., Stein, M., Robertson, C., Levin, H., Dikmen, S., Temkin, N., Barber, J., Giacino, J., Mukherjee, P., Wang, K., Okonkwo, D., Markowitz, A., Jain, S., Lowenstein, D., Manley, G., Diaz-Arrastia, R., Badjatia, N., Duhaime, A., Feeser, V., Gaudette, E., Gopinath, S., Keene, C., Korley, F., Madden, C., Merchant, R., Schnyer, D., & Zafonte, R. (2021). Association of Posttraumatic Epilepsy With 1-Year Outcomes After Traumatic Brain Injury. JAMA Network Open, 4 (12), e2140191. doi:10.1001/jamanetworkopen.2021.40191
Callaway, E., Dong, H., Ecker, J., Hawrylycz, M., Huang, Z., Lein, E., Ngai, J., Osten, P., Ren, B., Tolias, A., White, O., Zeng, H., Zhuang, X., Ascoli, G., Behrens, M., Chun, J., Feng, G., Gee, J., Ghosh, S., Halchenko, Y., Hertzano, R., Lim, B., Martone, M., Ng, L., Pachter, L., Ropelewski, A., Tickle, T., Yang, X., Zhang, K., Bakken, T., Berens, P., Daigle, T., Harris, J., Jorstad, N., Kalmbach, B., Kobak, D., Li, Y., Liu, H., Matho, K., Mukamel, E., Naeemi, M., Scala, F., Tan, P., Ting, J., Xie, F., Zhang, M., Zhang, Z., Zhou, J., Zingg, B., Armand, E., Yao, Z., Bertagnolli, D., Casper, T., Crichton, K., Dee, N., Diep, D., Ding, S., Dong, W., Dougherty, E., Fong, O., Goldman, M., Goldy, J., Hodge, R., Hu, L., Keene, C., Krienen, F., Kroll, M., Lake, B., Lathia, K., Linnarsson, S., Liu, C., Macosko, E., McCarroll, S., McMillen, D., Nadaf, N., Nguyen, T., Palmer, C., Pham, T., Plongthongkum, N., Reed, N., Regev, A., Rimorin, C., Romanow, W., Savoia, S., Siletti, K., Smith, K., Sulc, J., Tasic, B., Tieu, M., Torkelson, A., Tung, H., van Velthoven, C., Vanderburg, C., Yanny, A., Fang, R., Hou, X., Lucero, J., Osteen, J., Pinto-Duarte, A., Poirion, O., Preissl, S., Wang, X., Aldridge, A., Bartlett, A., Boggeman, L., O’Connor, C., Castanon, R., Chen, H., Fitzpatrick, C., Luo, C., Nery, J., Nunn, M., Rivkin, A., Tian, W., Dominguez, B., Ito-Cole, T., Jacobs, M., Jin, X., Lee, C., Lee, K., Miyazaki, P., Pang, Y., Rashid, M., Smith, J., Vu, M., Williams, E., Biancalani, T., Booeshaghi, A., Crow, M., Dudoit, S., Fischer, S., Gillis, J., Hu, Q., Kharchenko, P., Niu, S., Ntranos, V., Purdom, E., Risso, D., de Bézieux, H., Somasundaram, S., Street, K., Svensson, V., Vaishnav, E., Van den Berge, K., Welch, J., An, X., Bateup, H., Bowman, I., Chance, R., Foster, N., Galbavy, W., Gong, H., Gou, L., Hatfield, J., Hintiryan, H., Hirokawa, K., Kim, G., Kramer, D., Li, A., Li, X., Luo, Q., Muñoz-Castañeda, R., Stafford, D., Feng, Z., Jia, X., Jiang, S., Jiang, T., Kuang, X., Larsen, R., Lesnar, P., Li, Y., Li, Y., Liu, L., Peng, H., Qu, L., Ren, M., Ruan, Z., Shen, E., Song, Y., Wakeman, W., Wang, P., Wang, Y., Wang, Y., Yin, L., Yuan, J., Zhao, S., Zhao, X., Narasimhan, A., Palaniswamy, R., Banerjee, S., Ding, L., Huilgol, D., Huo, B., Kuo, H., Laturnus, S., Li, X., Mitra, P., Mizrachi, J., Wang, Q., Xie, P., Xiong, F., Yu, Y., Eichhorn, S., Berg, J., Bernabucci, M., Bernaerts, Y., Cadwell, C., Castro, J., Dalley, R., Hartmanis, L., Horwitz, G., Jiang, X., Ko, A., Miranda, E., Mulherkar, S., Nicovich, P., Owen, S., Sandberg, R., Sorensen, S., Tan, Z., Allen, S., Hockemeyer, D., Lee, A., Veldman, M., Adkins, R., Ament, S., Bravo, H., Carter, R., Chatterjee, A., Colantuoni, C., Crabtree, J., Creasy, H., Felix, V., Giglio, M., Herb, B., Kancherla, J., Mahurkar, A., McCracken, C., Nickel, L., Olley, D., Orvis, J., Schor, M., Hood, G., Dichter, B., Grauer, M., Helba, B., Bandrowski, A., Barkas, N., Carlin, B., D’Orazi, F., Degatano, K., Gillespie, T., Khajouei, F., Konwar, K., Thompson, C., Kelly, K., Mok, S., & Sunkin, S. (2021). A multimodal cell census and atlas of the mammalian primary motor cortex. Nature, 598 (7879), 86-102. doi:10.1038/s41586-021-03950-0
Campagnola, L., Seeman, S., Chartrand, T., Kim, L., Hoggarth, A., Gamlin, C., Ito, S., Trinh, J., Davoudian, P., Radaelli, C., Kim, M., Hage, T., Braun, T., Alfiler, L., Andrade, J., Bohn, P., Dalley, R., Henry, A., Kebede, S., Alice, M., Sandman, D., Williams, G., Larsen, R., Teeter, C., Daigle, T., Berry, K., Dotson, N., Enstrom, R., Gorham, M., Hupp, M., Dingman Lee, S., Ngo, K., Nicovich, P., Potekhina, L., Ransford, S., Gary, A., Goldy, J., McMillen, D., Pham, T., Tieu, M., Siverts, L., Walker, M., Farrell, C., Schroedter, M., Slaughterbeck, C., Cobb, C., Ellenbogen, R., Gwinn, R., Keene, C., Ko, A., Ojemann, J., Silbergeld, D., Carey, D., Casper, T., Crichton, K., Clark, M., Dee, N., Ellingwood, L., Gloe, J., Kroll, M., Sulc, J., Tung, H., Wadhwani, K., Brouner, K., Egdorf, T., Maxwell, M., McGraw, M., Pom, C., Ruiz, A., Bomben, J., Feng, D., Hejazinia, N., Shi, S., Szafer, A., Wakeman, W., Phillips, J., Bernard, A., Esposito, L., D’Orazi, F., Sunkin, S., Smith, K., Tasic, B., Arkhipov, A., Sorensen, S., Lein, E., Koch, C., Murphy, G., Zeng, H., & Jarsky, T. (2022). Local connectivity and synaptic dynamics in mouse and human neocortex. Science, 375, 6585. doi:10.1126/science.abj5861
Cheng, Z., Lozier, C. C., Lewis, M., O’Neil, M., Luoma, J. B., & Morasco, B. (2021). Investigating the role of psychological inflexibility, mindfulness, and self -compassion in PTSD. Journal of Contextual Behavioral Science, 22, 102-107.
Clouston, S., Hall, C., Kritikos, M., Bennett, D., DeKosky, S., Edwards, J., Finch, C., Kreisl, W., Mielke, M., Peskind, E. R., Raskind, M. A., Richards, M., Sloan, R., Spiro, A., Vasdev, N., Brackbill, R., Farfel, M., Horton, M., Lowe, S., Lucchini, R., Prezant, D., Reibman, J., Rosen, R., Seil, K., Zeig-Owens, R., Deri, Y., Diminich, E., Fausto, B., Gandy, S., Sano, M., Bromet, E., & Luft, B. (2022). Cognitive impairment and World Trade Centre-related exposures. Nature Reviews Neurology, 18 (2), 103-116. doi:10.1038/s41582-021-00576-8
Coffey, K. R., Lesiak, A., Marx, R., Vo, E., Garden, G., & Neumaier, J. F. (2022). A cAMP-Related Gene Network in Microglia Is Inversely Regulated by Morphine Tolerance and Withdrawal. Biological Psychiatry Global Open Science, 2(2), 180-189. doi:10.1016/j.bpsgos.2021.07.011
Coffey, K. R., Venkat, V., West, M. O., & Barker, D. J. (2021). Lateral preoptic area neurons signal cocaine self-administration behaviors. European Journal of Neuroscience, 54(7), 6397-6405.
Course, M., Gudsnuk, K., Keene, C., Bird, T., Jayadev, S., & Valdmanis, P. (2022). Aberrant splicing of PSEN2, but not PSEN1, in individuals with sporadic Alzheimer's disease. Brain. Advance online publication. doi:10.1093/brain/awac294
Damodarasamy, M., Khaing, Z., Hyde, J., Keene, C., Bentov, I., Banks, W., & Reed, M. (2022). Viable human brain microvessels for the study of aging and neurodegenerative diseases. Microvascular Research, 140, 104282. doi:10.1016/j.mvr.2021.104282
Dickstein, D., De Gasperi, R., Gama Sosa, M., Perez-Garcia, G., Short, J., Sosa, H., Perez, G., Tschiffely, A., Dams-O’Connor, K., Pullman, M., Knesaurek, K., Knutsen, A., Pham, D., Soleimani, L., Jordan, B., Gordon, W., Delman, B., Shumyatsky, G., Shahim, P., DeKosky, S., Stone, J., Peskind, E. R., Blennow, K., Zetterberg, H., Chance, S., Torso, M., Kostakoglu, L., Sano, M., Hof, P., Ahlers, S., Gandy, S., & Elder, G. (2021). Brain and blood biomarkers of tauopathy and neuronal injury in humans and rats with neurobehavioral syndromes following blast exposure. Molecular Psychiatry, 26 (10), 5940-5954. doi:10.1038/s41380-020-0674-z
Djerdjaj, A., Ng, A. J., Rieger, N. S., & Christianson, J. P. (2022). The basolateral amygdala to posterior insular cortex tract is necessary for social interaction with stressed juvenile rats. Behavioural brain research, 435, 114050. doi:10.1016/j.bbr.2022
Edelman, W., Kiianitsa, K., Virmani, T., Martinez, R., Young, J., Keene, C., Bird, T., Raskind, W., & Korvatska, O. (2022). Reduced gene dosage is a common mechanism of neuropathologies caused by ATP6AP2 splicing mutations. Parkinsonism & Related Disorders, 101, 31-38. doi:10.1016/j.parkreldis.2022.06.015
Eissman, J., Dumitrescu, L., Mahoney, E., Smith, A., Mukherjee, S., Lee, M., Scollard, P., Choi, S., Bush, W., Engelman, C., Lu, Q., Fardo, D., Trittschuh, E., Mez, J., Kaczorowski, C., Hernandez Saucedo, H., Widaman, K., Buckley, R., Properzi, M., Mormino, E., Yang, H., Harrison, T., Hedden, T., Nho, K., Andrews, S., Tommet, D., Hadad, N., Sanders, R., Ruderfer, D., Gifford, K., Zhong, X., Raghavan, N., Vardarajan, B., Pericak-Vance, M., Farrer, L., Wang, L., Cruchaga, C., Schellenberg, G., Cox, N., Haines, J., Keene, C., Saykin, A., Larson, E., Sperling, R., Mayeux, R., Cuccaro, M., Bennett, D., Schneider, J., Crane, P., Jefferson, A., & Hohman, T. (2022). Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease. Brain, 145 (7), 2541-2554. doi:10.1093/brain/awac177
Elliott, J., McBride, A., Balba, N., Thomas, S., Pattinson, C., Morasco, B., Wilkerson, A., Gill, J., & Lim, M. (2022). Feasibility and preliminary efficacy for morning bright light therapy to improve sleep and plasma biomarkers in US Veterans with TBI. A prospective, open-label, single-arm trial. PLOS ONE, 17 (4), e0262955. doi:10.1371/journal.pone.0262955
Evans, K., Barton, R., Hendrickson, R. C., & LaPlante, L. (2022). Creating Safe Spaces for Those Who Have Lived through Intimate Partner Violence. Journal of Aggression, Maltreatment & Trauma, NA, 1-16. doi:10.1080/10926771.2022.2099774
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Piantino, J., Iliff, J. J., & Lim, M. (2022). The Bidirectional Link Between Sleep Disturbances and Traumatic Brain Injury Symptoms: A Role for Glymphatic Dysfunction?. Biological Psychiatry, 91(5), 478-487. doi:10.1016/j.biopsych.2021.06.025
Prater, K., Green, K., Chiou, K., Smith, C., Sun, W., Shojaie, A., Heath, L., Rose, S., Keene, C., Logsdon, B., Snyder-Mackler, N., Blue, E., Young, J., Garden, G., & Jayadev, S. (2021). Microglia subtype transcriptomes differ between Alzheimer Disease and control human postmortem brain samples. Alzheimer's and Dementia, 17 (S2), e058474. doi:10.1002/alz.058474
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Salman, M., Kitchen, P., Halsey, A., Wang, M., Törnroth-Horsefield, S., Conner, A., Badaut, J., Iliff, J. J., & Bill, R. (2022). Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis. Brain, 145 (1), 64-75. doi:10.1093/brain/awab311
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Schneider, L., Bennett, D., Farlow, M., Peskind, E. R., Raskind, M. A., Sano, M., Stern, Y., Haneline, S., Welsh-Bohmer, K., O’Neil, J., Walter, R., Maresca, S., Culp, M., Alexander, R., Saunders, A., Burns, D., & Chiang, C. (2022). Adjudicating Mild Cognitive Impairment Due to Alzheimer’s Disease as a Novel Endpoint Event in the TOMMORROW Prevention Clinical Trial. The Journal of Prevention of Alzheimer's Disease, 9(4), 625-634. doi:10.14283/jpad.2022.72
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Simon, M., Wang, M., Ismail, O., Braun, M., Schindler, A., Reemmer, J., Wang, Z., Haveliwala, M., O’Boyle, R., Han, W., Roese, N., Grafe, M., Woltjer, R., Boison, D., & Iliff, J. J. (2022). Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid ß plaque formation in mice. Alzheimer's Research and Therapy, 14 (1), 59. doi:10.1186/s13195-022-00999-5
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VA VISN 20 consists of four states across three time zones; Alaska, Idaho, Oregon, and Washington. The primary research center located at VA Puget Sound Health Care System (VAPSHCS) is affiliated with University of Washington (UW). VAPSHCS serves Veterans from a five-state area in the Pacific Northwest with two main divisions: American Lake and Seattle. Veterans in Washington are also served by VA Medical Centers in Spokane, Vancouver, and Walla Walla. In Washington, there are VA Community Based Outpatient Clinics (CBOC's) located in Bellevue, Bremerton, Chehalis, Edmunds, Everett, Federal Way, Mount Vernon, Olympia, Port Angeles, Puyallup, Richland, Renton, Silverdale, Seattle, Wenatchee, and Yakima. The research center located at VA Portland Heath Care System (VAPORHCS) is affiliated with Oregon Health and Science University (OHSU). VAPORHCS serves Veterans from Oregon and Southwest Washington with two main divisions: Portland and Vancouver. Veterans in Oregon are also served by VA Medical Centers in Roseburg and White City. In Oregon, there are CBOC's located in Bend, Boardman, Brookings, Enterprise, Eugene, Fairview, Grants Pass, Hines, Hillsboro, Klamath Falls, LaGrande, Lincoln City, Newport, Portland, Salem, The Dalles, Warrenton, and West Linn. VA provides health care for Veterans from providers in your local community outside of VA. Veterans may be eligible to receive care from a community provider when VA cannot provide the care needed.
Vet Centers in the VISN 20 Health Care Network are community-based counseling centers that provide a wide range of social and psychological services, including professional readjustment counseling to eligible Veterans, active-duty Army, Navy, Marine Corps, Coast Guard, Air Force, and Space Force service members, including National Guard and Reserve components, and their families. 1-877-WAR-VETS is an around the clock confidential call center where Veterans, service members and their families can talk about their military experience or any other issue they are facing in transitioning after military service or trauma and get connected to their nearest Vet Center.
Veterans Crisis "988" - The Military Crisis Line is a free, confidential resource for all service members, including members of the National Guard and Reserve, and Veterans, even if they’re not enrolled in VA benefits or health care. Call 988 then Press 1 If you are a Veteran, service member, or any person concerned about one who is hard of hearing, you can connect with professional, caring VA responders through online chat and text message (838255).
In Europe
Call 00800 1273 8255 or DSN 118
In Korea
Call 080-855-5118 or DSN 118
In Afghanistan
Call 00 1 800 273 8255 or DSN 111
In the Philippines
Call #MYVA or 02-8550-3888 and press 7
A Veteran overseas may contact the Veterans Crisis Line via the chat modality at VeteransCrisisLine.net/Chat. If the Veteran prefers a phone call, they can request this within the chat venue. For TTY users: Use your preferred relay service or dial 711 then 1-800-273-8255. Are you looking for clinical care or counseling? Assistance with benefits? No matter what you’re experiencing, we’re here to connect you with resources and support systems to help. The Veterans Crisis Line is free and confidential. When you call, chat, or text, a qualified responder will listen and help. You decide how much information to share. Support doesn't end with your conversation. Our responders can connect you with the resources you need.
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VA has a variety of mental health resources, information, treatment options, and more — all accessible to Veterans, Veterans’ supporters, and the general public. Explore the pages below to learn more about a specific mental health topic. Each of these pages includes resources, information on treatment options, and more.
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For Daniel, Don, and Jennifer, convenient video counseling made it easier to put their health first. Adjusting from military service to civilian life can be both exciting and challenging. Make the Connection
Dial 988 then press 1
Connect with the Veterans Crisis Line to reach caring, qualified responders with the Department of Veterans Affairs. The Veterans Crisis Line is free and confidential. Support doesn't end with your conversation. Our responders can connect you with the resources you need.
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Explore the latest mental health news, resources, and real-life stories of mental health recovery.